point mutation

1. Mutations can be a change in a single base of DNA ( point mutation) or a loss of base pairs ( deletion) affecting a single gene, or a movement of chromosomal regions ( translocation) affecting many genes.
   突变可以是DNA的单个碱基变化（点突变）或一个基因中的一对碱基对丢失（缺失突变），或染色体的一段移位从而影响很多基因。
2. Point Mutation Detection Using Ligase-mediated Induced Fluorescence Resonance Energy Transfer
   连接酶介导的诱导荧光共振能量转移法检测基因点突变
3. Retinoblastoma Point mutation Polgmerase chain reaction Sequence analysis;
   点突变；聚合酶链反应；
4. However, several problems, such as the conservation and distribution of point mutation, remain to be clarified.
   但仍有一些问题，如突变的保守性和分布，需要进一步研究、阐明。
5. To reach this goal, the following ways such as chemical modification, gene fusion, point mutation and delivery systems revolution are reviewed.
   综述了几种多肽药物常用的长效改造方法如化学修饰、基因融合、点突变以及药物制剂释放系统的改造。
6. Another hot point mutation of Wilson disease gene in Chinese: exon 12
   肝豆状核变性基因12号外显子突变特征的研究
7. Study of Mitochondrial DNA Point Mutation in Patients with Basal Ganglia Calcification on Cranial CT
   脑CT示基底节钙化者的线粒体DNA突变研究
8. The Significance of γ-Carboxyglutamic Acid in Urinary Calcium Oxalate Stone Formation Point mutation of mitochondrial tRNA Leu ( UUR) gene in Chinese diabetics
   γ-羧基谷氨酸在草酸钙尿石形成中的意义线粒体转运核糖核酸亮氨酸基因异常与糖尿病
9. A Novel Point Mutation of K-ras Gene Coexisted with Codon 12 Mutation
   一个新的与12位密码子共存的K-ras基因突变位点
10. Construction, point mutation correction and expression of eukaryotic expression vectors for retinoic acid nuclear receptor
    维甲酸核受体RARα真核表达载体的构建、突变纠正及表达
11. Work in understanding the role of RNA in the cell. Point mutation of mitochondrial tRNA Leu ( UUR) gene in Chinese diabetics
    对核糖酸（RNA）细胞中作用认识的研究。线粒体转运核糖核酸亮氨酸基因异常与糖尿病
12. In BCR-ABL fusion gene negative myeloproliferative diseases, the discovery of JAK2V617F point mutation is an important landmark.
    在BCR-ABL阴性的骨髓增殖性疾病的发病机制中，JAK2V617F点突变的发现是一个重大的突破。
13. Point mutation of mitochondrial tRNA Leu ( UUR) gene in Chinese diabetics Study on Zinc Absorption and Metabolism of Zinc Amino Acid Chelate and Effecting Factors
    线粒体转运核糖核酸亮氨酸基因异常与糖尿病氨基酸螯合锌吸收、转运特点和影响因素的研究
14. PCR-SSCP was a convenient and efficient method to detect gene point mutation.
    PCR-SSCP是检测基因点突变的一种快速、敏感、有效的方法。
15. The expression of ras P21 was consistent with point mutation in codon 12 of Ha-ras oncogene.
    Ha－ras癌基因第12位密码子点突变与rasp21的表达是一致的。
16. Establishment of PCR amplification and method for the detection of MBL point mutation ( PCR-RFLP);
    方法PCR扩增，测定序列并建立MBL基因点突变检测方法，即PCRRFLP方法（BanⅠ酶切）；
17. The ratio of point mutation in codon 12 of H-ras is low in gastric cancer.
    胃癌组织中H-ras基因第12密码子点突变率低，在胃癌的发生中不起主要作用。
18. Applying RNase Protection assay, the point mutation in the RB gene was observed.
    运用核酸酶保护试验观察RB基因的点突变现象。
19. Recently, we have developed an electrochemiluminescence-polymerase chain reaction ( ECL-PCR) method for point mutation detection.
    近年来发展了一种用于定量检测基因点突变的电化学发光PCR方法。
20. Point mutation of K-ras gene in pancreatic carcinoma
    胰腺癌组织中K－ras基因点突变的研究
21. There was no exon deletion and point mutation in normal controls.
    正常人中未发现外显子缺失和点突变。
22. Analysis of k-ras point mutation in human colorectal cancer cell lines HR 8348 and HCe 8693
    人大肠癌细胞系HR8348和HCe8693K－ras基因的点突变分析
23. Some genetic diseases, such as hemophilia B, are partly caused by a given point mutation.
    一些遗传性疾病，如乙型血友病，有部分是由于Ⅸ因子核苷酸序列中特定位点点突变引起的。
24. A study on the relationship of point mutation of ras oncogenes with prognosis of patients with gastric cancer
    胃癌组织中ras基因点突变和病人预后关系的研究
25. Missense mutation or point mutation;
    无义突变或点突变；
26. Detection of gene point mutation is an important method on analysis of cancer occurrence.
    基因的点突变在癌症的发生中起重要的作用，检测基冈点突变成为分析癌症发生的重要手段。
27. Nine of the 10 sites were point mutation and 1 of the 10 was insert mutation.
    10个突变中9个为点突变，1个为插入突变。

noun

1. (genetics) a mutation due to an intramolecular reorganization of a gene

   Synonym:    gene mutation